Massachusetts State Police say high school students and their adult chaperones were on a charter bus after a visit to Harvard University when the oversized bus crashed into a bridge in Boston.

Dream Foundation bus that hit an overpass in Boston (Boston Fire Department)

The bus crashed about 7:30 p.m. Saturday as it was passing under a bridge on Soldier's Field Road, a major crosstown road. The Destined for a Dream Foundation group was returning to the Philadelphia area.

The injured, three seriously, were taken to hospitals.

Authorities say the bus did not belong on that road and state police are investigating whether charges are warranted against the driver after apparently failing to see the sign prohibiting the vehicle from taking that route.

Raymond Talmedge, the owner of Calvary Coach told WPVI TV, "He said he looked at the GPS, looked down to make the turn and when he looked back up, the bridge was a low bridge, he hit the low bridge," said Talmedge, who said his driver was being interviewed by police.

Firefighters say they needed to remove the roof of the bus to treat 4 injured passengers who were trapped for over an hour reports WCVB TV.

The Destined for a Dream Foundation is a non-profit organization that provides higher education services to students in Bucks and Montgomery and Philadelphia counties.